Overweight and obesity may lead to under-diagnosis of airflow limitation: findings from the Copenhagen City Heart Study.

Yunus Çolak, Jacob Louis Marott, Jørgen Vestbo, Peter Lange

    Research output: Contribution to journalArticlepeer-review

    Abstract

    BACKGROUND: The prevalence of obesity has increased during the last decades and varies from 10-20% in most European countries to approximately 32% in the United States. However, data on how obesity affects the presence of airflow limitation (AFL) defined as a reduced ratio between forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) are scarce. METHODS: Data was derived from the third examination of the Copenhagen City Heart Study from 1991 until 1994 (n = 10,135). We examine the impact of different adiposity markers (weight, body mass index (BMI), waist circumference, waist-hip ratio, and abdominal height) on AFL. AFL was defined in four ways: FEV1/FVC ratio <0.70, FEV1/FVC ratio <lower limit of normal (LLN), FEV1/FVC ratio
    Original languageEnglish
    JournalCOPD
    Volume12
    Issue number1
    DOIs
    Publication statusPublished - Feb 2015

    Keywords

    • airflow limitation
    • airway obstruction
    • body mass index
    • chronic obstructive pulmonary disease
    • diagnosis
    • epidemiology
    • lower limit of normal
    • lung function
    • obesity
    • spirometry

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