p53 Codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia

A. N. Rosenthal; A. Ryan; D. Hopster; I. J. Jacobs

doi:10.1054/bjoc.2000.1419

p53 Codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia

A. N. Rosenthal, A. Ryan, D. Hopster, I. J. Jacobs

Research output: Contribution to journal › Article › peer-review

Abstract

p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia. (C) 2000 Cancer Research Campaign.

Original language	English
Pages (from-to)	1287-1290
Number of pages	3
Journal	British Journal of Cancer
Volume	83
Issue number	10
DOIs	https://doi.org/10.1054/bjoc.2000.1419
Publication status	Published - 2000

Keywords

p53
Polymorphism
VIN
Vulval cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1054/bjoc.2000.1419

Cite this

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title = "p53 Codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia",

abstract = "p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia. (C) 2000 Cancer Research Campaign.",

keywords = "p53, Polymorphism, VIN, Vulval cancer",

author = "Rosenthal, {A. N.} and A. Ryan and D. Hopster and Jacobs, {I. J.}",

year = "2000",

doi = "10.1054/bjoc.2000.1419",

language = "English",

volume = "83",

pages = "1287--1290",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Springer Nature",

number = "10",

}

TY - JOUR

T1 - p53 Codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia

AU - Rosenthal, A. N.

AU - Ryan, A.

AU - Hopster, D.

AU - Jacobs, I. J.

PY - 2000

Y1 - 2000

N2 - p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia. (C) 2000 Cancer Research Campaign.

AB - p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia. (C) 2000 Cancer Research Campaign.

KW - p53

KW - Polymorphism

KW - VIN

KW - Vulval cancer

U2 - 10.1054/bjoc.2000.1419

DO - 10.1054/bjoc.2000.1419

M3 - Article

C2 - 11044351

SN - 0007-0920

VL - 83

SP - 1287

EP - 1290

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 10

ER -

p53 Codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia

Abstract

Keywords

UN SDGs

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