Pain pathways and pre-emptive and protective analgesia for oral surgery

P. Coulthard, E. Bailey, N. Patel, M. B. Coulthard

    Research output: Contribution to journalArticlepeer-review


    Aim: To describe the scientific basis of the contemporary management of pain after oral surgery. Materials and methods: A review of the literature describing the concepts of pre-emptive and protective analgesia and evidence-based practice in the context of managing pain after oral surgery. Results: Pain is the consequence of the interplay of numerous chemical mediators and a dynamic and plastic neuronal system, and so pain prevention and management requires the use of different classes of analgesic that act by different mechanisms and at different sites of action, ideally resulting in synergistic analgesia with few side effects. Conclusions: Management can be challenging, particularly as much oral surgery is undertaken on an outpatient and day-case basis, but significant improvement can be made to the patient's experience by considering the underlying mechanisms. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
    Original languageEnglish
    Pages (from-to)74-80
    Number of pages6
    JournalOral Surgery
    Issue number2
    Publication statusPublished - 2014


    • Oral
    • Pain
    • Surgery


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