Pain symptoms in depression: Definition and clinical significance

Cornelius Katona, Robert Reveler, Christopher Dowrick, Simon Wessely, Charlotte Feinmann, Linda Gask, Huw Lloyd, Amanda C De C Williams, Elizabeth Wager

    Research output: Contribution to journalArticlepeer-review


    This article presents the findings of a focused literature review and consensus meetings on the definition and clinical significance of painful symptoms in patients with depression. About 50% of depressed patients report pain, and many types of pain occur more frequently in people with depression than in those without. There is some evidence that pain in depressed patients is associated with a poor response to treatment. Pain and depression may share common pathways and may both respond to treatment with certain antidepressants. Doctors need to be alert to pain in depressed patients and be prepared to treat it.
    Original languageEnglish
    Pages (from-to)390-395
    Number of pages5
    JournalClinical Medicine, Journal of the Royal College of Physicians of London
    Issue number4
    Publication statusPublished - Jul 2005


    • Comorbidity
    • Consensus
    • Definition
    • Depression
    • Pain


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