Abstract
Background: Overshoot of weight regain following the treatment of hyperthyroidism is well described. Notwithstanding, there is a large interindividual variability in the observed weight changes. This study aims to identify parameters predicting excessive weight gain in hyperthyroidism patients.
Methods: In a retrospective study of a prospectively completed database, we recruited consecutive patients with overt hyperthyroidism and compared those with excessive weight gain (≥10%, Group A) to those with less gain (<10%, Group B) based on initial anthropometrics, demographics, and disease-related characteristics, using appropriate statistical tests.
Results: We recruited 91 patients (70.3% females, median age 50 years) treated for hyperthyroidism with a median follow-up of 2 years. Excessive weight gain (GpA) was observed in 50% of patients. GpA had significantly higher ft4 levels and disease-related weight loss at presentation.
Conclusion: The severity of thyrotoxicosis and the disease-related weight loss were predictive of excessive weight gain post-treatment. This information alongside the presentation BMI may allow risk stratification for excessive weight gain, hereby permitting early intervention strategies.
Methods: In a retrospective study of a prospectively completed database, we recruited consecutive patients with overt hyperthyroidism and compared those with excessive weight gain (≥10%, Group A) to those with less gain (<10%, Group B) based on initial anthropometrics, demographics, and disease-related characteristics, using appropriate statistical tests.
Results: We recruited 91 patients (70.3% females, median age 50 years) treated for hyperthyroidism with a median follow-up of 2 years. Excessive weight gain (GpA) was observed in 50% of patients. GpA had significantly higher ft4 levels and disease-related weight loss at presentation.
Conclusion: The severity of thyrotoxicosis and the disease-related weight loss were predictive of excessive weight gain post-treatment. This information alongside the presentation BMI may allow risk stratification for excessive weight gain, hereby permitting early intervention strategies.
Original language | English |
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DOIs | |
Publication status | Published - 13 Nov 2023 |
Event | Society for Endocrinology BES 2023 - Glasgow, United Kingdom Duration: 13 Nov 2023 → 15 Nov 2023 https://www.endocrinology.org/events/sfe-bes-conference/sfe-bes-2023/ |
Conference
Conference | Society for Endocrinology BES 2023 |
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Country/Territory | United Kingdom |
City | Glasgow |
Period | 13/11/23 → 15/11/23 |
Internet address |