Partial deletion of the Saccharomyces cerevisiae GDH3 gene results in novel starvation phenotypes

Barrie M. Wilkinson; Carolyn M. James; Richard M. Walmsley

Partial deletion of the Saccharomyces cerevisiae GDH3 gene results in novel starvation phenotypes

Barrie M. Wilkinson, Carolyn M. James, Richard M. Walmsley

Research output: Contribution to journal › Article › peer-review

Abstract

A small-scale functional analysis screen has revealed several new phenotypes associated with a large deletion of GDH3, one of two Saccharomyces cerevisiae genes known to encode NADP-linked glutamate dehydrogenase. Diploids heterozygous for the deletion are able to sporulate in rich media, while haploid deletants produce dark, wrinkled colonies containing pseudohyphal cells. The haploid cells rapidly lose viability upon starvation.

Original language	English
Pages (from-to)	1667-1673
Number of pages	6
Journal	Microbiology
Volume	142
Issue number	7
Publication status	Published - Jul 1996

Keywords

Foraging
GDH3
Nitrogen metabolism
PolyGT
Starvation

Cite this

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title = "Partial deletion of the Saccharomyces cerevisiae GDH3 gene results in novel starvation phenotypes",

abstract = "A small-scale functional analysis screen has revealed several new phenotypes associated with a large deletion of GDH3, one of two Saccharomyces cerevisiae genes known to encode NADP-linked glutamate dehydrogenase. Diploids heterozygous for the deletion are able to sporulate in rich media, while haploid deletants produce dark, wrinkled colonies containing pseudohyphal cells. The haploid cells rapidly lose viability upon starvation.",

keywords = "Foraging, GDH3, Nitrogen metabolism, PolyGT, Starvation",

author = "Wilkinson, {Barrie M.} and James, {Carolyn M.} and Walmsley, {Richard M.}",

year = "1996",

month = jul,

language = "English",

volume = "142",

pages = "1667--1673",

journal = "Microbiology",

issn = "1350-0872",

publisher = "Microbiology Society",

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T1 - Partial deletion of the Saccharomyces cerevisiae GDH3 gene results in novel starvation phenotypes

AU - Wilkinson, Barrie M.

AU - James, Carolyn M.

AU - Walmsley, Richard M.

PY - 1996/7

Y1 - 1996/7

N2 - A small-scale functional analysis screen has revealed several new phenotypes associated with a large deletion of GDH3, one of two Saccharomyces cerevisiae genes known to encode NADP-linked glutamate dehydrogenase. Diploids heterozygous for the deletion are able to sporulate in rich media, while haploid deletants produce dark, wrinkled colonies containing pseudohyphal cells. The haploid cells rapidly lose viability upon starvation.

AB - A small-scale functional analysis screen has revealed several new phenotypes associated with a large deletion of GDH3, one of two Saccharomyces cerevisiae genes known to encode NADP-linked glutamate dehydrogenase. Diploids heterozygous for the deletion are able to sporulate in rich media, while haploid deletants produce dark, wrinkled colonies containing pseudohyphal cells. The haploid cells rapidly lose viability upon starvation.

KW - Foraging

KW - GDH3

KW - Nitrogen metabolism

KW - PolyGT

KW - Starvation

M3 - Article

C2 - 8757731

SN - 1350-0872

VL - 142

SP - 1667

EP - 1673

JO - Microbiology

JF - Microbiology

IS - 7

ER -

Partial deletion of the Saccharomyces cerevisiae GDH3 gene results in novel starvation phenotypes

Abstract

Keywords

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