Abstract
Over the years, the rising popularity of peptides has led to a paradigm shift in the focus of biotechnology and pharmaceutical industry from traditional molecular-based interventions to the development of multifaceted nanomaterial-based interventions. The ‘bench-to-bedside’ approach has enabled researchers to work with a variety of peptide-based bionanomaterials for applications in tissue engineering, regenerative medicine, drug delivery, biosensing and 3D printing, paving the way for clinical translation. Owing to the very nature of peptide molec-ular building blocks that form the basis of self-assembled biomaterials, the final materials exhibit extraordinary properties, such as biocompatibility, flexibility in design, reproducibility and stability, which help expedite their translation into different application domains within biomedicine. In this chapter, we highlight the clinical need for translation of peptide nanomaterials, outline current priority appli-cation areas and discuss how these are currently bridging gaps between academic and industrial research to support product development, scale up and adoption of technology. The chapter also outlines the substantial growth in global market size of peptide-based biomaterial products. Many examples of peptide nanomaterials include hydrogels as scaffolds and wound dressing materials; 3D printed nanostructures; and nanotubes as drug delivery vehicles and components for recon-struction of soft tissues and 3D cell culture. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.
| Original language | English |
|---|---|
| Title of host publication | Peptide Bionanomaterials: |
| Subtitle of host publication | From Design to Application |
| Editors | Mohamed A. Elsawy |
| Publisher | Springer Nature |
| Pages | 539-555 |
| Number of pages | 17 |
| ISBN (Print) | 9783031293603 , 9783031293597 |
| DOIs | |
| Publication status | Published - 2023 |
Keywords
- 3D printing
- Biomaterial global market
- Bionanomaterials
- Drug delivery
- Hydrogels
- Peptide
- Regenerative medicine
- Tissue engineering