Peptide-mediated cell delivery: Application in protein target validation

Mark A. Lindsay

    Research output: Contribution to journalArticlepeer-review


    Recent reports have suggested that conjugation of peptides, proteins and antisense to short highly basic peptides, such as TAT, antennapedia and transportan, results in their rapid translocation into cells. Importantly, these conjugates have been shown to exert actions in a number of animal models suggesting their general utility for the determination of protein function in vitro and in vivo.
    Original languageEnglish
    Pages (from-to)587-594
    Number of pages7
    JournalCurrent opinion in pharmacology
    Issue number5
    Publication statusPublished - 1 Oct 2002


    • Animals
    • administration & dosage: Antisense Elements (Genetics)
    • Cells
    • Drug Delivery Systems
    • Humans
    • administration & dosage: Peptides
    • administration & dosage: Proteins
    • metabolism: Receptors, Drug
    • drug effects: Signal Transduction


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