Personality variables are associated with colorectal cancer patients' quality of life independent of psychological distress and disease severity

Vassiliki Paika, Augoustina Almyroudi, Barbara Tomenson, Francis Creed, Eleftherios O. Kampletsas, Vassiliki Siafaka, Styliani Gkika, Venetsanos Mavreas, Nicholas Pavlidis, Thomas Hyphantis

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective: The aim of the present study was to test whether psychological distress and personality variables are independently associated with health-related quality of life (HRQOL) in colorectal cancer patients, after adjusting for age, gender, education and disease severity. Methods: In a cross-sectional study of 162 colorectal cancer patients (response rate 65.6%), the following self-report instruments were administered: the Symptom Distress Checklist-90-R, the Sense of Coherence scale, the Life Style Index and the Hostility and Direction of Hostility Questionnaire. The outcome measures were the four components of the WHO Quality of Life Instrument, Short Form. We used hierarchical regressions to determine whether psychological distress mediates the relationship of personality and disease parameters with HRQOL. Results: The overall proportion of the variance in the four components of HRQOL explained by our regression models ranged from 28.1 to 44.4%. Psychological distress was an independent correlate of HRQOL, associated with physical (p
    Original languageEnglish
    Pages (from-to)273-282
    Number of pages9
    JournalPsycho-oncology
    Volume19
    Issue number3
    DOIs
    Publication statusPublished - Mar 2010

    Keywords

    • Colorectal cancer
    • Ego mechanisms of defense
    • Oncology
    • Personality
    • Psychological distress
    • Quality of life
    • Sense of coherence

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