Pharmacogenetics in the management of breast cancer - Prospects for individualised treatment

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Increased understanding of how variants in genes encoding metabolising enzymes, transporters and receptors affect drug efficacy and toxicity, in parallel with advances in genotyping technology means that clinical pharmacogenetics is drawing tantalisingly close to reality. This review considers some of the pharmacogenetic variants that have been described that are relevant to the management of women with breast cancer and how these may soon translate into clinical practice. © Springer 2006.
    Original languageEnglish
    Pages (from-to)151-157
    Number of pages6
    JournalFamilial Cancer
    Volume5
    Issue number2
    DOIs
    Publication statusPublished - Jun 2006

    Keywords

    • Breast cancer
    • Pharmacogenetics

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