Photoinduced decarboxylative azidation of cyclic amino acids

David C. Marcote; Rosie Street-Jeakings; Elizabeth Dauncey; James J. Douglas; Alessandro Ruffoni; Daniele Leonori

doi:10.1039/c8ob02702a

Photoinduced decarboxylative azidation of cyclic amino acids

David C. Marcote, Rosie Street-Jeakings, Elizabeth Dauncey, James J. Douglas, Alessandro Ruffoni^*, Daniele Leonori

^*Corresponding author for this work

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Abstract

The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

Original language	English
Pages (from-to)	1839-1842
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	17
Issue number	7
Early online date	26 Dec 2018
DOIs	https://doi.org/10.1039/c8ob02702a
Publication status	Published - 1 Jan 2019

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Photoinduced Decarboxylative Azidation of Cyclic Amino AcidsSubmitted manuscript, 978 KB
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abstract = "The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.",

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AU - Marcote, David C.

AU - Street-Jeakings, Rosie

AU - Dauncey, Elizabeth

AU - Douglas, James J.

AU - Ruffoni, Alessandro

AU - Leonori, Daniele

PY - 2019/1/1

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N2 - The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

AB - The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

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U2 - 10.1039/c8ob02702a

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AN - SCOPUS:85061491790

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SP - 1839

EP - 1842

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

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Photoinduced decarboxylative azidation of cyclic amino acids

Abstract

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