Photoinduced decarboxylative azidation of cyclic amino acids

David C. Marcote, Rosie Street-Jeakings, Elizabeth Dauncey, James J. Douglas, Alessandro Ruffoni, Daniele Leonori

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    Abstract

    The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

    Original languageEnglish
    Pages (from-to)1839-1842
    Number of pages4
    JournalOrganic and Biomolecular Chemistry
    Volume17
    Issue number7
    Early online date26 Dec 2018
    DOIs
    Publication statusPublished - 1 Jan 2019

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