PII-059* Mechanistic Population Pharmacokinetic Modeling of Risdiplam for Extrapolation of Exposure and Cyp3a Drug-drug Interaction in Neonates with Spinal Muscular Atrophy

Y Cleary; H Kletzl; P Grimsey; K Heinig; K Ogungbenro; H Silber--Baumann; N Frey; L Aarons; A Galetin; M Gertz

doi:10.1002/cpt.2835

PII-059* Mechanistic Population Pharmacokinetic Modeling of Risdiplam for Extrapolation of Exposure and Cyp3a Drug-drug Interaction in Neonates with Spinal Muscular Atrophy

Y Cleary, H Kletzl, P Grimsey, K Heinig, K Ogungbenro, H Silber--Baumann, N Frey, L Aarons, A Galetin, M Gertz

Pharmacy

Research output: Contribution to journal › Meeting Abstract › peer-review

Original language	English
Pages (from-to)	S63
Number of pages	1
Journal	Clinical Pharmacology & Therapeutics
Volume	113
Early online date	16 Feb 2023
DOIs	https://doi.org/10.1002/cpt.2835
Publication status	Published - 1 Mar 2023
Event	American Society for Clinical Pharmacology and Therapeutics (ASCPT) 2023 Annual Meeting: Pre-Conference: Advancing the Utilization of Real-World Data (RWD) and Real-World Evidence (RWE) in Clinical Pharmacology and Translational Research - Atlanta, United States Duration: 21 Mar 2023 → 21 Mar 2023

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Cleary, Y., Kletzl, H., Grimsey, P., Heinig, K., Ogungbenro, K., Silber--Baumann, H., Frey, N., Aarons, L., Galetin, A., & Gertz, M. (2023). PII-059* Mechanistic Population Pharmacokinetic Modeling of Risdiplam for Extrapolation of Exposure and Cyp3a Drug-drug Interaction in Neonates with Spinal Muscular Atrophy. Clinical Pharmacology & Therapeutics, 113, S63. https://doi.org/10.1002/cpt.2835

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author = "Y Cleary and H Kletzl and P Grimsey and K Heinig and K Ogungbenro and H Silber--Baumann and N Frey and L Aarons and A Galetin and M Gertz",

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Cleary, Y, Kletzl, H, Grimsey, P, Heinig, K, Ogungbenro, K, Silber--Baumann, H, Frey, N, Aarons, L , Galetin, A & Gertz, M 2023, 'PII-059* Mechanistic Population Pharmacokinetic Modeling of Risdiplam for Extrapolation of Exposure and Cyp3a Drug-drug Interaction in Neonates with Spinal Muscular Atrophy', Clinical Pharmacology & Therapeutics, vol. 113, pp. S63. https://doi.org/10.1002/cpt.2835

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AU - Cleary, Y

AU - Kletzl, H

AU - Grimsey, P

AU - Heinig, K

AU - Ogungbenro, K

AU - Silber--Baumann, H

AU - Frey, N

AU - Aarons, L

AU - Galetin, A

AU - Gertz, M

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SN - 0009-9236

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JO - Clinical Pharmacology & Therapeutics

JF - Clinical Pharmacology & Therapeutics

T2 - American Society for Clinical Pharmacology and Therapeutics (ASCPT) 2023 Annual Meeting

Y2 - 21 March 2023 through 21 March 2023

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PII-059* Mechanistic Population Pharmacokinetic Modeling of Risdiplam for Extrapolation of Exposure and Cyp3a Drug-drug Interaction in Neonates with Spinal Muscular Atrophy

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