Placental Growth Factor Testing for Suspected Preeclampsia: a Cost-Minimisation Analysis

Kate E. Duhig, Paul T. Seed, Jenny Myers, Rachna Bahl, Gabrielle Bambridge, Sonia Barnfield, Jo Ficquet, Joanna Girling, Asma Khalil, Andrew Shennan, Lucy C Chappell, Rachael M. Hunter

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: to calculate the cost-savings associated with implementing Placental Growth Factor (PlGF) testing alongside a clinical management algorithm in maternity services in the United Kingdom, compared to current standard care.
Design: cost minimisation analysis.
Setting: 11 maternity units participating in the PARROT stepped wedge cluster randomised controlled trial.
Population: women presenting with suspected pre-eclampsia between 20+0 and 36+6 weeks’ gestation.
Methods: Monte Carlo simulation utilising resource use data
Main Outcome Measures: cost associated with PlGF implementation when compared to standard care.
Results: there is a total cost saving of £219 per pregnancy, £149 when including the cost of the test. This represents a potential cost saving of £2,891,196 each year across the English NHS.
Conclusions: PlGF testing is associated with the potential for cost savings per participant tested when compared to current practice. This economic analysis supports a role for implementation of PlGF testing into antenatal services for the assessment of women with suspected preeclampsia.
Original languageEnglish
JournalBJOG
Publication statusAccepted/In press - 1 Jul 2019

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