Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.

S. Valpione; Gabriela Gremel; Piyushkumar Mundra; Elena Galvani; Maria Girotti; Rebecca Lee; G. Garner; Nathalie Dhomen; Paul Lorigan; Richard Marais

doi:10.1016/j.ejca.2017.10.029

Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.

S. Valpione, Gabriela Gremel, Piyushkumar Mundra, Elena Galvani, Maria Girotti, Rebecca Lee, G. Garner, Nathalie Dhomen, Paul Lorigan, Richard Marais

Research output: Contribution to journal › Article › peer-review

Abstract

Original language	English
Journal	European Journal of Cancer
Early online date	23 Nov 2017
DOIs	https://doi.org/10.1016/j.ejca.2017.10.029
Publication status	Published - 2017

Keywords

melanoma
total circulating cell-free DNA
tumour burden
Prognostic biomarker

Research Beacons, Institutes and Platforms

Manchester Cancer Research Centre

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ejca.2017.10.029Licence: CC BY

Embargoed Document

Manuscript_tumour_burden
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Embargo ends: 1/01/27

Cite this

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title = "Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.",

keywords = "melanoma, total circulating cell-free DNA, tumour burden, Prognostic biomarker",

author = "S. Valpione and Gabriela Gremel and Piyushkumar Mundra and Elena Galvani and Maria Girotti and Rebecca Lee and G. Garner and Nathalie Dhomen and Paul Lorigan and Richard Marais",

year = "2017",

doi = "10.1016/j.ejca.2017.10.029",

language = "English",

journal = "European Journal of Cancer",

issn = "0959-8049",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.

AU - Valpione, S.

AU - Gremel, Gabriela

AU - Mundra, Piyushkumar

AU - Galvani, Elena

AU - Girotti, Maria

AU - Lee, Rebecca

AU - Garner, G.

AU - Dhomen, Nathalie

AU - Lorigan, Paul

AU - Marais, Richard

PY - 2017

Y1 - 2017

KW - melanoma

KW - total circulating cell-free DNA

KW - tumour burden

KW - Prognostic biomarker

U2 - 10.1016/j.ejca.2017.10.029

DO - 10.1016/j.ejca.2017.10.029

M3 - Article

SN - 0959-8049

JO - European Journal of Cancer

JF - European Journal of Cancer

ER -