Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.

S. Valpione, Gabriela Gremel, Piyushkumar Mundra, Elena Galvani, Maria Girotti, Rebecca Lee, G. Garner, Nathalie Dhomen, Paul Lorigan, Richard Marais

Research output: Contribution to journalArticlepeer-review


Original languageEnglish
JournalEuropean Journal of Cancer
Early online date23 Nov 2017
Publication statusPublished - 2017


  • melanoma
  • total circulating cell-free DNA
  • tumour burden
  • Prognostic biomarker

Research Beacons, Institutes and Platforms

  • Manchester Cancer Research Centre

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