The oral route for delivery of pharmaceuticals is the most widely used and accepted. Nanoparticles and microparticles are increasingly being applied within this arena to optimize drug targeting and bioavailability. Frequently the carrier systems used are either constructed from or contain polymeric materials. Examples of these nanocarriers include polymeric nanoparticles, solid lipid nanocarriers, self-nanoemulsifying drug delivery systems and nanocrystals. It is the purpose of this review to describe these cutting edge technologies and specifically focus on the interaction and fate of these polymers within the gastrointestinal system. © 2012 Elsevier Inc.
|Journal||Nanomedicine: Nanotechnology, Biology, and Medicine|
|Publication status||Published - Sep 2012|
- Gastrointestinal tract
- Oral drug delivery
- Peyers's patch