Potential neurologic manifestations of COVID-19

Anna S  Nordvig; Kathryn T Rimmer; Joshua Z Willey; Kiran T Thakur; Amelia K  Boehme; Wendy S Vargas; Craig Smith; Mitchell S V Elkind

doi:10.1212/CPJ.0000000000000897

Potential neurologic manifestations of COVID-19

Anna S Nordvig, Kathryn T Rimmer, Joshua Z Willey, Kiran T Thakur, Amelia K Boehme, Wendy S Vargas, Craig Smith, Mitchell S V Elkind

Division of Cardiovascular Sciences (L5)

Columbia University

Research output: Contribution to journal › Article › peer-review

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Abstract

Purpose of review: Neurological complications are increasingly recognized in the Coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This coronavirus is related to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and other human coronavirus-related illnesses that are associated with neurological symptoms. These symptoms raise the question of a neuroinvasive potential of SARS-CoV-2.

Recent findings: Potential neurological symptoms and syndromes of SARS-CoV-2 include headache, fatigue, dizziness, anosmia, ageusia, anorexia, myalgias, meningoencephalitis, hemorrhage, altered consciousness, Guillain-Barré Syndrome, syncope, seizure, and stroke. Additionally, we discuss neurological effects of other coronaviruses, special considerations for management of neurological patients, and possible long-term neurological and public health sequelae.

Summary: As SARS-CoV-2 is projected to infect a large part of the world’s population, understanding the potential neurological implications of COVID-19 will help neurologists and others recognize and intervene in neurological morbidity during and after the pandemic of 2020.

Original language	English
Journal	Neurology Clinical Practice
Early online date	30 Jun 2020
DOIs	https://doi.org/10.1212/CPJ.0000000000000897
Publication status	E-pub ahead of print - 30 Jun 2020

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Lydia Becker Institute

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CPJ.0000000000000897.fullAccepted author manuscript, 3.79 MB

Cite this

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title = "Potential neurologic manifestations of COVID-19",

abstract = "Purpose of review: Neurological complications are increasingly recognized in the Coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This coronavirus is related to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and other human coronavirus-related illnesses that are associated with neurological symptoms. These symptoms raise the question of a neuroinvasive potential of SARS-CoV-2.Recent findings: Potential neurological symptoms and syndromes of SARS-CoV-2 include headache, fatigue, dizziness, anosmia, ageusia, anorexia, myalgias, meningoencephalitis, hemorrhage, altered consciousness, Guillain-Barr{\'e} Syndrome, syncope, seizure, and stroke. Additionally, we discuss neurological effects of other coronaviruses, special considerations for management of neurological patients, and possible long-term neurological and public health sequelae.Summary: As SARS-CoV-2 is projected to infect a large part of the world{\textquoteright}s population, understanding the potential neurological implications of COVID-19 will help neurologists and others recognize and intervene in neurological morbidity during and after the pandemic of 2020.",

author = "Nordvig, {Anna S} and Rimmer, {Kathryn T} and Willey, {Joshua Z} and Thakur, {Kiran T} and Boehme, {Amelia K} and Vargas, {Wendy S} and Craig Smith and Elkind, {Mitchell S V}",

year = "2020",

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day = "30",

doi = "10.1212/CPJ.0000000000000897",

language = "English",

journal = "Neurology Clinical Practice",

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T1 - Potential neurologic manifestations of COVID-19

AU - Nordvig, Anna S

AU - Rimmer, Kathryn T

AU - Willey, Joshua Z

AU - Thakur, Kiran T

AU - Boehme, Amelia K

AU - Vargas, Wendy S

AU - Smith, Craig

AU - Elkind, Mitchell S V

PY - 2020/6/30

Y1 - 2020/6/30

N2 - Purpose of review: Neurological complications are increasingly recognized in the Coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This coronavirus is related to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and other human coronavirus-related illnesses that are associated with neurological symptoms. These symptoms raise the question of a neuroinvasive potential of SARS-CoV-2.Recent findings: Potential neurological symptoms and syndromes of SARS-CoV-2 include headache, fatigue, dizziness, anosmia, ageusia, anorexia, myalgias, meningoencephalitis, hemorrhage, altered consciousness, Guillain-Barré Syndrome, syncope, seizure, and stroke. Additionally, we discuss neurological effects of other coronaviruses, special considerations for management of neurological patients, and possible long-term neurological and public health sequelae.Summary: As SARS-CoV-2 is projected to infect a large part of the world’s population, understanding the potential neurological implications of COVID-19 will help neurologists and others recognize and intervene in neurological morbidity during and after the pandemic of 2020.

AB - Purpose of review: Neurological complications are increasingly recognized in the Coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This coronavirus is related to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and other human coronavirus-related illnesses that are associated with neurological symptoms. These symptoms raise the question of a neuroinvasive potential of SARS-CoV-2.Recent findings: Potential neurological symptoms and syndromes of SARS-CoV-2 include headache, fatigue, dizziness, anosmia, ageusia, anorexia, myalgias, meningoencephalitis, hemorrhage, altered consciousness, Guillain-Barré Syndrome, syncope, seizure, and stroke. Additionally, we discuss neurological effects of other coronaviruses, special considerations for management of neurological patients, and possible long-term neurological and public health sequelae.Summary: As SARS-CoV-2 is projected to infect a large part of the world’s population, understanding the potential neurological implications of COVID-19 will help neurologists and others recognize and intervene in neurological morbidity during and after the pandemic of 2020.

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DO - 10.1212/CPJ.0000000000000897

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SN - 2163-0402

JO - Neurology Clinical Practice

JF - Neurology Clinical Practice

ER -

Potential neurologic manifestations of COVID-19

Abstract

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