Power surge: Supporting cells "fuel" cancer cell mitochondria

Ubaldo E. Martinez-Outschoorn; Federica Sotgia; Michael P. Lisanti

doi:10.1016/j.cmet.2011.12.011

Power surge: Supporting cells "fuel" cancer cell mitochondria

Ubaldo E. Martinez-Outschoorn, Federica Sotgia, Michael P. Lisanti

Research output: Contribution to journal › Article › peer-review

Abstract

An emerging paradigm in tumor metabolism is that catabolism in host cells "fuels" the anabolic growth of cancer cells via energy transfer. A study in Nature Medicine (Nieman et al., 2011) supports this; they show that triglyceride catabolism in adipocytes drives ovarian cancer metastasis by providing fatty acids as mitochondrial fuels. © 2012 Elsevier Inc.

Original language	English
Pages (from-to)	4-5
Number of pages	1
Journal	Cell Metabolism
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.cmet.2011.12.011
Publication status	Published - 4 Jan 2012

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10.1016/j.cmet.2011.12.011

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abstract = "An emerging paradigm in tumor metabolism is that catabolism in host cells {"}fuels{"} the anabolic growth of cancer cells via energy transfer. A study in Nature Medicine (Nieman et al., 2011) supports this; they show that triglyceride catabolism in adipocytes drives ovarian cancer metastasis by providing fatty acids as mitochondrial fuels. {\textcopyright} 2012 Elsevier Inc.",

author = "Martinez-Outschoorn, {Ubaldo E.} and Federica Sotgia and Lisanti, {Michael P.}",

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AU - Lisanti, Michael P.

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AB - An emerging paradigm in tumor metabolism is that catabolism in host cells "fuels" the anabolic growth of cancer cells via energy transfer. A study in Nature Medicine (Nieman et al., 2011) supports this; they show that triglyceride catabolism in adipocytes drives ovarian cancer metastasis by providing fatty acids as mitochondrial fuels. © 2012 Elsevier Inc.

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Power surge: Supporting cells "fuel" cancer cell mitochondria

Abstract

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