Practical de-O-acylation reactions promoted by molecular sieves

K.P.R. Kartha, B. Mukhopadhyay, R.A. Field

Research output: Contribution to journalArticlepeer-review


Methanol dried extensively over molecular sieves, or methanol in combination with powdered molecular sieves, serves as a good acceptor for acyl transfer reactions. Several O-acetylated and O-benzoylated sugar derivatives were efficiently de-O-acylated using this approach. In the case of per-O-acetylated N-acetylglucosamine, selective anomeric deprotection could be effected in high yield.
Original languageUndefined
Pages (from-to)729-732
Number of pages3
JournalCarbohydrate Research
Issue number3
Publication statusPublished - 25 Feb 2004


  • Molecular sieves
  • Alcohols
  • Deacetylation

Research Beacons, Institutes and Platforms

  • Manchester Institute of Biotechnology

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