Abstract
The technique of cell immobilization using porous support particles (biomass support particles) has been successfully applied to yeast cells. Two reactor configurations exploiting the use of these particles have been developed and assessed for use in aseptic yeast fermentations. A liquid-fluidized bed fermenter has been devised for use with particles denser than the fermentation liquor while a gas-stirred circulating bed fermenter proved suitable for particles of essentially neutral buoyancy. Both systems have been operated successfully for extended periods of continuous operation.
| Original language | English |
|---|---|
| Pages (from-to) | 134-141 |
| Number of pages | 7 |
| Journal | Biotechnology and Bioengineering |
| Volume | 26 |
| Issue number | 2 |
| Publication status | Published - Feb 1984 |