Preclinical pharmacology of AZD5363, an inhibitor of AKT: Pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background

  • Barry R. Davies
  • , Hannah Greenwood
  • , Phillippa Dudley
  • , Claire Crafter
  • , De Hua Yu
  • , Jingchuan Zhang
  • , Jing Li
  • , Beirong Gao
  • , Qunsheng Ji
  • , Juliana Maynard
  • , Sally Ann Ricketts
  • , Darren Cross
  • , Sabina Cosulich
  • , Christine C. Chresta
  • , Ken Page
  • , James Yates
  • , Clare Lane
  • , Rebecca Watson
  • , Richard Luke
  • , Donald Ogilvie
  • Martin Pass

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Pharmacology, Toxicology and Pharmaceutical Science