Prescribing antidepressants for depression: time to be dimensional and inclusive

Ian M Anderson, Peter M Haddad

Research output: Contribution to journalArticlepeer-review


The article by Middleton and Moncrieff questions the role of antidepressants in treating depression on both philosophical and practical grounds; namely that depression isn't a brain disease to be treated by a drug and that antidepressants are ineffective except as placebos. We argue that their stance is unhelpful and factually incorrect and that a more dimensional and integrative approach is needed in order to be able to best tailor treatment to individual needs. This involves a personalised assessment of the likely benefits and risks of both psychological and drug approaches when recommending treatment for someone with depression. ©British Journal of General Practice.
Original languageEnglish
Pages (from-to)50-52
Number of pages3
JournalBritish Journal of General Practice
Issue number582
Publication statusPublished - Jan 2011


  • Antidepressive Agents
  • Depressive Disorder
  • Humans
  • Psychotherapy
  • Randomized Controlled Trials as Topic
  • Treatment Outcome
  • Journal Article


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