PRINTS and PRINTS-S shed light on protein ancestry

T. K. Attwood; M. J. Blythe; D. R. Flower; A. Gaulton; J. E. Mabey; N. Maudling; L. McGregor; A. L. Mitchell; G. Moulton; K. Paine; P. Scordis; Jane Gilsenan

doi:10.1093/nar/30.1.239

PRINTS and PRINTS-S shed light on protein ancestry

T. K. Attwood, M. J. Blythe, D. R. Flower, A. Gaulton, J. E. Mabey, N. Maudling, L. McGregor, A. L. Mitchell, G. Moulton, K. Paine, P. Scordis, Jane Gilsenan

Bio-Health Informatics

Research output: Contribution to journal › Article › peer-review

Abstract

The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September 2001 release (version 32.0) includes 1600 fingerprints, encoding ∼10 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here its use as a source of annotation in the InterPro resource, and the use of its relational cousin, PRINTS-S, to model relationships between families, including those beyond the reach of conventional sequence analysis approaches. The database is accessible for BLAST, fingerprint and text searches at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.

Original language	English
Pages (from-to)	239-241
Number of pages	2
Journal	Nucleic acids research.
Volume	30
Issue number	1
DOIs	https://doi.org/10.1093/nar/30.1.239
Publication status	Published - 1 Jan 2002

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title = "PRINTS and PRINTS-S shed light on protein ancestry",

abstract = "The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September 2001 release (version 32.0) includes 1600 fingerprints, encoding ∼10 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here its use as a source of annotation in the InterPro resource, and the use of its relational cousin, PRINTS-S, to model relationships between families, including those beyond the reach of conventional sequence analysis approaches. The database is accessible for BLAST, fingerprint and text searches at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.",

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doi = "10.1093/nar/30.1.239",

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TY - JOUR

T1 - PRINTS and PRINTS-S shed light on protein ancestry

AU - Attwood, T. K.

AU - Blythe, M. J.

AU - Flower, D. R.

AU - Gaulton, A.

AU - Mabey, J. E.

AU - Maudling, N.

AU - McGregor, L.

AU - Mitchell, A. L.

AU - Moulton, G.

AU - Paine, K.

AU - Scordis, P.

AU - Gilsenan, Jane

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September 2001 release (version 32.0) includes 1600 fingerprints, encoding ∼10 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here its use as a source of annotation in the InterPro resource, and the use of its relational cousin, PRINTS-S, to model relationships between families, including those beyond the reach of conventional sequence analysis approaches. The database is accessible for BLAST, fingerprint and text searches at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.

AB - The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September 2001 release (version 32.0) includes 1600 fingerprints, encoding ∼10 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here its use as a source of annotation in the InterPro resource, and the use of its relational cousin, PRINTS-S, to model relationships between families, including those beyond the reach of conventional sequence analysis approaches. The database is accessible for BLAST, fingerprint and text searches at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.

U2 - 10.1093/nar/30.1.239

DO - 10.1093/nar/30.1.239

M3 - Article

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SN - 1362-4962

VL - 30

SP - 239

EP - 241

JO - Nucleic acids research.

JF - Nucleic acids research.

IS - 1

ER -

PRINTS and PRINTS-S shed light on protein ancestry

Abstract

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