Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory

H. Fersi; P. Gardner; M. Surman; N. Scrutton; M. Scutliffe

Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory

H. Fersi^*
, P. Gardner
, M. Surman
, N. Scrutton
, M. Scutliffe

^*Corresponding author for this work

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

Abstract

There is a general interest in developing a new research field linking new powerful sources of THz radiation with key contemporary challenges in protein science; Specifically, the highly controversial role of fast protein promoting vibrations in biological catalysis. However, the 1 - 10 THz region of the electromagnetic spectrum is particularly difficult to access experimentally due to the low intensity of conventional laboratory based sources. Therefore we developed a THz radiation station using the existing accelerator based sources on the SRS at Daresbury. We recorded spectra incorporating the low frequency collective vibrations of small molecules as well as some proteins in the solid state. Our experiments were carried out using non-coherent radiation from the modified THz testing facility (TTF) on the SRS at Daresbury.

Original language	English
Title of host publication	IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics
Pages	393-394
Number of pages	2
Publication status	Published - 2007
Event	Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007 - Cardiff, United Kingdom Duration: 3 Sept 2007 → 7 Sept 2007

Conference

Conference	Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007
Country/Territory	United Kingdom
City	Cardiff
Period	3/09/07 → 7/09/07

Keywords

Hydrogen tunneling
Protein catalysis
Synchrotron sources
Terahertz radiation

Cite this

Fersi, H., Gardner, P., Surman, M., Scrutton, N., & Scutliffe, M. (2007). Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory. In IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics (pp. 393-394). Article 4516548

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title = "Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory",

abstract = "There is a general interest in developing a new research field linking new powerful sources of THz radiation with key contemporary challenges in protein science; Specifically, the highly controversial role of fast protein promoting vibrations in biological catalysis. However, the 1 - 10 THz region of the electromagnetic spectrum is particularly difficult to access experimentally due to the low intensity of conventional laboratory based sources. Therefore we developed a THz radiation station using the existing accelerator based sources on the SRS at Daresbury. We recorded spectra incorporating the low frequency collective vibrations of small molecules as well as some proteins in the solid state. Our experiments were carried out using non-coherent radiation from the modified THz testing facility (TTF) on the SRS at Daresbury.",

keywords = "Hydrogen tunneling, Protein catalysis, Synchrotron sources, Terahertz radiation",

author = "H. Fersi and P. Gardner and M. Surman and N. Scrutton and M. Scutliffe",

year = "2007",

language = "English",

isbn = "1424414385",

pages = "393--394",

booktitle = "IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics",

note = "Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007 ; Conference date: 03-09-2007 Through 07-09-2007",

}

Fersi, H, Gardner, P, Surman, M, Scrutton, N & Scutliffe, M 2007, Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory. in IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics., 4516548, pp. 393-394, Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007, Cardiff, United Kingdom, 3/09/07.

Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory. / Fersi, H.; Gardner, P.; Surman, M. et al.
IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics. 2007. p. 393-394 4516548.

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory

AU - Fersi, H.

AU - Gardner, P.

AU - Surman, M.

AU - Scrutton, N.

AU - Scutliffe, M.

PY - 2007

Y1 - 2007

N2 - There is a general interest in developing a new research field linking new powerful sources of THz radiation with key contemporary challenges in protein science; Specifically, the highly controversial role of fast protein promoting vibrations in biological catalysis. However, the 1 - 10 THz region of the electromagnetic spectrum is particularly difficult to access experimentally due to the low intensity of conventional laboratory based sources. Therefore we developed a THz radiation station using the existing accelerator based sources on the SRS at Daresbury. We recorded spectra incorporating the low frequency collective vibrations of small molecules as well as some proteins in the solid state. Our experiments were carried out using non-coherent radiation from the modified THz testing facility (TTF) on the SRS at Daresbury.

AB - There is a general interest in developing a new research field linking new powerful sources of THz radiation with key contemporary challenges in protein science; Specifically, the highly controversial role of fast protein promoting vibrations in biological catalysis. However, the 1 - 10 THz region of the electromagnetic spectrum is particularly difficult to access experimentally due to the low intensity of conventional laboratory based sources. Therefore we developed a THz radiation station using the existing accelerator based sources on the SRS at Daresbury. We recorded spectra incorporating the low frequency collective vibrations of small molecules as well as some proteins in the solid state. Our experiments were carried out using non-coherent radiation from the modified THz testing facility (TTF) on the SRS at Daresbury.

KW - Hydrogen tunneling

KW - Protein catalysis

KW - Synchrotron sources

KW - Terahertz radiation

UR - https://www.scopus.com/pages/publications/77951164604

M3 - Conference contribution

AN - SCOPUS:77951164604

SN - 1424414385

SN - 9781424414383

SP - 393

EP - 394

BT - IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics

T2 - Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007

Y2 - 3 September 2007 through 7 September 2007

ER -

Fersi H, Gardner P, Surman M, Scrutton N, Scutliffe M. Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory. In IRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics. 2007. p. 393-394. 4516548

Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory

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