Probing the mobility of catenane rings in single molecules

Anne Van Quaethem, Perrine Lussis, David A. Leigh, Anne Sophie Duwez, Charles André Fustin

    Research output: Contribution to journalArticlepeer-review


    Here we demonstrate for the first time the interrogation of a mechanical link made of catenane rings at the single molecule level. We used AFM-based single molecule force spectroscopy to address the mobility of the rings in a catenane unit of the benzylic amide family. To interface the catenane with the AFM probe, we connected a polymer chain to each of the macrocycles of the [2]catenane. Force-extension profiles in different solvents were then recorded. We show that the catenane ring motions can be detected at the single molecule level and that the ring rotation can be locked or unlocked depending on the solvent. © 2014 The Royal Society of Chemistry.
    Original languageEnglish
    Pages (from-to)1449-1452
    Number of pages3
    JournalChemical Science
    Issue number4
    Publication statusPublished - Apr 2014


    Dive into the research topics of 'Probing the mobility of catenane rings in single molecules'. Together they form a unique fingerprint.

    Cite this