Prodromal signs of relapse in schizophrenia

N. Tarrier, C. Barrowclough, J. S. Bamrah

    Research output: Contribution to journalArticlepeer-review


    Fifty-six patients who were hospitalised for a schizophrenic episode were followed up for nine months after discharge. The Psychiatric Assessment Scale (PAS, Krawiecka et al., 1977) was administered at monthly intervals during this period. Twenty-three patients relapsed of which data were available for sixteen. In these sixteen patients who relapsed comparisons were made of the PAS symptoms between the month prior to relapse and the month preceding this. Sixteen patients who did not relapse were randomly matched with the relapsing patients and an index point comparable in time to relapse onset in the matched relapsed patient was identified. Comparisons were made on the PAS symptoms using a repeated measures ANOVA to compare relapsers and non relapsers on the month prior to relapse and the month which preceded this. Discriminant function analysis was used to predict relapse by analysis of those PAS symptoms which showed an increase in the month before relapse. This suggested that the measures of depression and hallucinations significantly increased in the month prior to relapse compared to the preceding month in relapsers but not non-relapsers. The results of this study closely agree with previous published results even though there were some differences between studies in the patient samples.
    Original languageEnglish
    Pages (from-to)157-161
    Number of pages4
    JournalSocial psychiatry and psychiatric epidemiology
    Issue number4
    Publication statusPublished - 1991


    • Adolescent
    • Adult
    • Female
    • Follow-Up Studies
    • Hospitalization
    • Humans
    • Male
    • Middle Aged
    • Psychiatric Status Rating Scales
    • Recurrence
    • diagnosis: Schizophrenia
    • Schizophrenic Psychology


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