Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes

Alexander S. Jones; James Austerberry; Rana Dajani; James Warwicker; Robin Curtis; Jeremy Derrick; Colin  Robinson

doi:10.1016/j.bbamcr.2016.09.006

Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes

Alexander S. Jones, James Austerberry, Rana Dajani, James Warwicker, Robin Curtis, Jeremy Derrick, Colin Robinson

University of Kent

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3116-3124
Number of pages	9
Journal	Biochimica et Biophysica Acta - Proteins and Proteomics
Volume	1863
Issue number	12
Early online date	9 Sept 2016
DOIs	https://doi.org/10.1016/j.bbamcr.2016.09.006
Publication status	Published - Dec 2016

Access to Document

10.1016/j.bbamcr.2016.09.006

https://www.researchgate.net/publication/308091156_Proofreading_of_substrate_structure_by_the_Twin-Arginine_Translocase_is_highly_dependent_on_substrate_conformational_flexibility_but_surprisingly_tolerant_of_surface_charge_and_hydrophobicity_changes

Cite this

Jones, A. S., Austerberry, J., Dajani, R., Warwicker, J., Curtis, R., Derrick, J., & Robinson, C. (2016). Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes. Biochimica et Biophysica Acta - Proteins and Proteomics, 1863(12), 3116-3124. https://doi.org/10.1016/j.bbamcr.2016.09.006

@article{4a7e2253699b4469ad091f9d49102271,

title = "Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes",

author = "Jones, {Alexander S.} and James Austerberry and Rana Dajani and James Warwicker and Robin Curtis and Jeremy Derrick and Colin Robinson",

year = "2016",

month = dec,

doi = "10.1016/j.bbamcr.2016.09.006",

language = "English",

volume = "1863",

pages = "3116--3124",

journal = "Biochimica et Biophysica Acta - Proteins and Proteomics",

issn = "1570-9639",

publisher = "Elsevier BV",

number = "12",

}

Jones, AS, Austerberry, J, Dajani, R, Warwicker, J , Curtis, R , Derrick, J & Robinson, C 2016, 'Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes', Biochimica et Biophysica Acta - Proteins and Proteomics, vol. 1863, no. 12, pp. 3116-3124. https://doi.org/10.1016/j.bbamcr.2016.09.006

Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes. / Jones, Alexander S.; Austerberry, James; Dajani, Rana et al.
In: Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1863, No. 12, 12.2016, p. 3116-3124.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes

AU - Jones, Alexander S.

AU - Austerberry, James

AU - Dajani, Rana

AU - Warwicker, James

AU - Curtis, Robin

AU - Derrick, Jeremy

AU - Robinson, Colin

PY - 2016/12

Y1 - 2016/12

U2 - 10.1016/j.bbamcr.2016.09.006

DO - 10.1016/j.bbamcr.2016.09.006

M3 - Article

SN - 1570-9639

VL - 1863

SP - 3116

EP - 3124

JO - Biochimica et Biophysica Acta - Proteins and Proteomics

JF - Biochimica et Biophysica Acta - Proteins and Proteomics

IS - 12

ER -

Jones AS, Austerberry J, Dajani R, Warwicker J , Curtis R , Derrick J et al. Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes. Biochimica et Biophysica Acta - Proteins and Proteomics. 2016 Dec;1863(12):3116-3124. Epub 2016 Sept 9. doi: 10.1016/j.bbamcr.2016.09.006