Protein adsorption studied by neutron reflection

Jian R. Lu; Xiubo Zhao; Mohammed Yaseen

doi:10.1016/j.cocis.2007.02.001

Protein adsorption studied by neutron reflection

Jian R. Lu, Xiubo Zhao, Mohammed Yaseen

Research output: Contribution to journal › Article › peer-review

Abstract

This article reviews recent development in the use of neutron reflection to study protein adsorption. The phenomenon of protein adsorption will be introduced, followed by the outline of the technological relevance of the interfacial molecular events. As lysozyme and albumins are widely used in recent adsorption studies, these model systems will be taken to demonstrate how interfacial structural details are affected by different surface chemical nature. The prospect of neutron reflection in revealing interfacial structural conformations of biologically more relevant proteins is highlighted. © 2007.

Original language	English
Pages (from-to)	9-16
Number of pages	7
Journal	Current Opinion in Colloid and Interface Science
Volume	12
Issue number	1
DOIs	https://doi.org/10.1016/j.cocis.2007.02.001
Publication status	Published - Feb 2007

Keywords

Denaturation
ECM proteins
Enzyme immobilisation
Interface
Neutron reflection
Protein adsorption
Protein surfactant
Protein unfolding
Surface
Surface cleaning
Thin films

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10.1016/j.cocis.2007.02.001

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title = "Protein adsorption studied by neutron reflection",

abstract = "This article reviews recent development in the use of neutron reflection to study protein adsorption. The phenomenon of protein adsorption will be introduced, followed by the outline of the technological relevance of the interfacial molecular events. As lysozyme and albumins are widely used in recent adsorption studies, these model systems will be taken to demonstrate how interfacial structural details are affected by different surface chemical nature. The prospect of neutron reflection in revealing interfacial structural conformations of biologically more relevant proteins is highlighted. {\textcopyright} 2007.",

keywords = "Denaturation, ECM proteins, Enzyme immobilisation, Interface, Neutron reflection, Protein adsorption, Protein surfactant, Protein unfolding, Surface, Surface cleaning, Thin films",

author = "Lu, {Jian R.} and Xiubo Zhao and Mohammed Yaseen",

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AU - Lu, Jian R.

AU - Zhao, Xiubo

AU - Yaseen, Mohammed

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AB - This article reviews recent development in the use of neutron reflection to study protein adsorption. The phenomenon of protein adsorption will be introduced, followed by the outline of the technological relevance of the interfacial molecular events. As lysozyme and albumins are widely used in recent adsorption studies, these model systems will be taken to demonstrate how interfacial structural details are affected by different surface chemical nature. The prospect of neutron reflection in revealing interfacial structural conformations of biologically more relevant proteins is highlighted. © 2007.

KW - Denaturation

KW - ECM proteins

KW - Enzyme immobilisation

KW - Interface

KW - Neutron reflection

KW - Protein adsorption

KW - Protein surfactant

KW - Protein unfolding

KW - Surface

KW - Surface cleaning

KW - Thin films

U2 - 10.1016/j.cocis.2007.02.001

DO - 10.1016/j.cocis.2007.02.001

M3 - Article

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SP - 9

EP - 16

JO - Current Opinion in Colloid and Interface Science

JF - Current Opinion in Colloid and Interface Science

IS - 1

ER -

Protein adsorption studied by neutron reflection

Abstract

Keywords

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