Proteomics of the human malaria parasite Plasmodium falciparum

Paul F G Sims; John E. Hyde

doi:10.1586/14789450.3.1.87

Proteomics of the human malaria parasite Plasmodium falciparum

Paul F G Sims, John E. Hyde

Research output: Contribution to journal › Article › peer-review

Abstract

The lethal species of malaria parasite, Plasmodium falciparum, continues to exact a huge toll of mortality and morbidity, particularly in sub-Saharan Africa. Completion of the genome sequence of this organism and advances in proteomics and mass spectrometry have opened up unprecedented opportunities for understanding the complex biology of this parasite and how it responds to drug challenge and other interventions. This review describes recent progress that has been made in applying proteomics technology to this important pathogen and provides a look forward to likely future developments. © 2006 Future Drugs Ltd.

Original language	English
Pages (from-to)	87-95
Number of pages	8
Journal	Expert review of proteomics
Volume	3
Issue number	1
DOIs	https://doi.org/10.1586/14789450.3.1.87
Publication status	Published - 2006

Keywords

Cell cycle
Drug challenge
Mass spectrometry
Metabolic labeling
Post-translational modifications
Quantitative proteomics
Subproteome analysis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1586/14789450.3.1.87

http://www.future-drugs.com/doi/pdf/10.1586/14789450.3.1.87

Cite this

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AB - The lethal species of malaria parasite, Plasmodium falciparum, continues to exact a huge toll of mortality and morbidity, particularly in sub-Saharan Africa. Completion of the genome sequence of this organism and advances in proteomics and mass spectrometry have opened up unprecedented opportunities for understanding the complex biology of this parasite and how it responds to drug challenge and other interventions. This review describes recent progress that has been made in applying proteomics technology to this important pathogen and provides a look forward to likely future developments. © 2006 Future Drugs Ltd.

KW - Cell cycle

KW - Drug challenge

KW - Mass spectrometry

KW - Metabolic labeling

KW - Post-translational modifications

KW - Quantitative proteomics

KW - Subproteome analysis

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Proteomics of the human malaria parasite Plasmodium falciparum

Abstract

Keywords

UN SDGs

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