Provision of gastroprotective medication and bleeding risk following acute coronary syndrome

Athar Badar; Jennifer Scaife; Andrew T. Yan; Simon D. Robinson; Azfar G. Zaman; Ian F. Purcell; Javed M. Ahmed; Mohaned Egred; Richard J. Edwards; Ioakim Spyridopoulos; Bernard D. Keavney; Alan J. Bagnall

Provision of gastroprotective medication and bleeding risk following acute coronary syndrome

Athar Badar, Jennifer Scaife, Andrew T. Yan, Simon D. Robinson, Azfar G. Zaman, Ian F. Purcell, Javed M. Ahmed, Mohaned Egred, Richard J. Edwards, Ioakim Spyridopoulos, Bernard D. Keavney, Alan J. Bagnall

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Gastrointestinal (GI) bleeding following percutaneous coronary intervention (PCI) is associated with increased mortality. ACCF/AHA/SCAI guidelines recommend prophylaxis to prevent GI bleeding in patients, with the highest GI bleeding risks taking dual-antiplatelet therapy (DAPT). The REPLACE risk score identifies factors predictive of peri-PCI bleeding from vascular access and non-access sites. We determined whether high bleeding risk acute coronary syndrome (ACS) patients taking DAPT were appropriately provided with GI prophylaxis and investigated the association between age and clinical presentation on the likelihood of receiving prophylactic therapy. METHODS: This is a retrospective analysis of all non-elective PCI patients at a single center between May and December 2008 stratified by age (

Original language	English
Pages (from-to)	397-401
Number of pages	4
Journal	Journal of Invasive Cardiology
Volume	25
Issue number	8
Publication status	Published - Aug 2013

Keywords

acute coronary syndrome
bleeding
delivery of care
risk stratification

Cite this

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title = "Provision of gastroprotective medication and bleeding risk following acute coronary syndrome",

abstract = "BACKGROUND: Gastrointestinal (GI) bleeding following percutaneous coronary intervention (PCI) is associated with increased mortality. ACCF/AHA/SCAI guidelines recommend prophylaxis to prevent GI bleeding in patients, with the highest GI bleeding risks taking dual-antiplatelet therapy (DAPT). The REPLACE risk score identifies factors predictive of peri-PCI bleeding from vascular access and non-access sites. We determined whether high bleeding risk acute coronary syndrome (ACS) patients taking DAPT were appropriately provided with GI prophylaxis and investigated the association between age and clinical presentation on the likelihood of receiving prophylactic therapy. METHODS: This is a retrospective analysis of all non-elective PCI patients at a single center between May and December 2008 stratified by age (",

keywords = "acute coronary syndrome, bleeding, delivery of care, risk stratification",

author = "Athar Badar and Jennifer Scaife and Yan, {Andrew T.} and Robinson, {Simon D.} and Zaman, {Azfar G.} and Purcell, {Ian F.} and Ahmed, {Javed M.} and Mohaned Egred and Edwards, {Richard J.} and Ioakim Spyridopoulos and Keavney, {Bernard D.} and Bagnall, {Alan J.}",

year = "2013",

month = aug,

language = "English",

volume = "25",

pages = "397--401",

journal = "Journal of Invasive Cardiology",

issn = "1557-2501",

publisher = "HMP Communications, LLC",

number = "8",

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TY - JOUR

T1 - Provision of gastroprotective medication and bleeding risk following acute coronary syndrome

AU - Badar, Athar

AU - Scaife, Jennifer

AU - Yan, Andrew T.

AU - Robinson, Simon D.

AU - Zaman, Azfar G.

AU - Purcell, Ian F.

AU - Ahmed, Javed M.

AU - Egred, Mohaned

AU - Edwards, Richard J.

AU - Spyridopoulos, Ioakim

AU - Keavney, Bernard D.

AU - Bagnall, Alan J.

PY - 2013/8

Y1 - 2013/8

N2 - BACKGROUND: Gastrointestinal (GI) bleeding following percutaneous coronary intervention (PCI) is associated with increased mortality. ACCF/AHA/SCAI guidelines recommend prophylaxis to prevent GI bleeding in patients, with the highest GI bleeding risks taking dual-antiplatelet therapy (DAPT). The REPLACE risk score identifies factors predictive of peri-PCI bleeding from vascular access and non-access sites. We determined whether high bleeding risk acute coronary syndrome (ACS) patients taking DAPT were appropriately provided with GI prophylaxis and investigated the association between age and clinical presentation on the likelihood of receiving prophylactic therapy. METHODS: This is a retrospective analysis of all non-elective PCI patients at a single center between May and December 2008 stratified by age (

AB - BACKGROUND: Gastrointestinal (GI) bleeding following percutaneous coronary intervention (PCI) is associated with increased mortality. ACCF/AHA/SCAI guidelines recommend prophylaxis to prevent GI bleeding in patients, with the highest GI bleeding risks taking dual-antiplatelet therapy (DAPT). The REPLACE risk score identifies factors predictive of peri-PCI bleeding from vascular access and non-access sites. We determined whether high bleeding risk acute coronary syndrome (ACS) patients taking DAPT were appropriately provided with GI prophylaxis and investigated the association between age and clinical presentation on the likelihood of receiving prophylactic therapy. METHODS: This is a retrospective analysis of all non-elective PCI patients at a single center between May and December 2008 stratified by age (

KW - acute coronary syndrome

KW - bleeding

KW - delivery of care

KW - risk stratification

M3 - Article

VL - 25

SP - 397

EP - 401

JO - Journal of Invasive Cardiology

JF - Journal of Invasive Cardiology

SN - 1557-2501

IS - 8

ER -

Provision of gastroprotective medication and bleeding risk following acute coronary syndrome

Abstract

Keywords

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