TY - PAT
T1 - PYRIMIDINE DERIVATIVES
AU - Kettle, Jason, Grant
AU - Read, Jon
AU - Leach, Andrew
AU - Barlaam, Bernard, Christophe
AU - Ducray, Richard
AU - Lambert-Van Der Brempt, Christine, Marie Paul
PY - 2007/8/2
Y1 - 2007/8/2
N2 - The invention concerns benzamide compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R, ring A, n, R, and R are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of EphB4, and/or EphA2 and/or Src kinases.
AB - The invention concerns benzamide compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R, ring A, n, R, and R are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of EphB4, and/or EphA2 and/or Src kinases.
M3 - Patent
M1 - WO2007085833
ER -