Quantification method using the Morlet wavelet for magnetic resonance spectroscopic signals with macromolecular contamination

Aimamorn Suvichakorn, Hélène Ratiney, Adriana Bucur, Sophie Cavassila, Jean-Pierre Antoine

Research output: Contribution to journalArticlepeer-review

Abstract

We study the Morlet wavelet transform on characterizing Magnetic Resonance Spectroscopic (MRS) signals acquired at short echo-time. These signals contain contributions from metabolites, water and a baseline which mainly originates from large molecules, known as macromolecules, and lipids. The baseline signal decays faster than the metabolite ones. Therefore, by making use of the time-scale representation of the wavelet, the two signals can be distinguished without any additional pre-processing. This is confirmed by the experimental results which show that the Morlet wavelet can correctly quantify the metabolite contributions even when a baseline is embedded in the MRS signals.

Keywords

  • Algorithms
  • Creatine
  • Fourier Analysis
  • Humans
  • Image Enhancement
  • Image Interpretation, Computer-Assisted
  • Lipids
  • Macromolecular Substances
  • Magnetic Resonance Spectroscopy
  • Models, Statistical
  • Phantoms, Imaging
  • Regression Analysis
  • Reproducibility of Results
  • Signal Processing, Computer-Assisted
  • Journal Article
  • Research Support, Non-U.S. Gov't

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