Quantification of spinal cord atrophy from magnetic resonance images via a B-spline active surface model

O. Coulon, S. J. Hickman, G. J. Parker, G. J. Barker, D. H. Miller, S. R. Arridge

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A method is presented that aims at segmenting and measuring the surface of the spinal cord from MR images in order to detect and quantify atrophy. A semiautomatic segmentation with very little intervention from an operator is proposed. It is based on the optimization of a B-spline active surface. The method allows for the computation of orthogonal cross-sections at any level along the cord, from which measurements are derived, such as cross-sectional area or curvature. An evaluation of the accuracy and reproducibility of the method is presented. © 2002 Wiley-Liss, Inc.
    Original languageEnglish
    Pages (from-to)1176-1185
    Number of pages9
    JournalMagnetic Resonance in Medicine
    Volume47
    Issue number6
    DOIs
    Publication statusPublished - 2002

    Keywords

    • Active surface
    • Atrophy
    • Multiple sclerosis
    • Spinal cord

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