Quantum catalysis in enzymes: Beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005

Nigel S. Scrutton; Michael J. Sutcliffe; P. Leslie Dutton

doi:10.1098/rsif.2006.0122

Quantum catalysis in enzymes: Beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005

Nigel S. Scrutton, Michael J. Sutcliffe, P. Leslie Dutton

Research output: Contribution to journal › Article › peer-review

Abstract

How do enzymes work? What is the physical basis of the phenomenal rate enhancements achieved by enzymes? Do we have a theoretical framework that accounts for observed catalytic rates? These are the foremost questions - with particular emphasis on tunnelling phenomena - debated at this Discussion Meeting by the leading practitioners in the field. © 2006 The Royal Society.

Original language	English
Pages (from-to)	465-469
Number of pages	4
Journal	Journal of the Royal Society Interface
Volume	3
Issue number	8
DOIs	https://doi.org/10.1098/rsif.2006.0122
Publication status	Published - 22 Jun 2006

Keywords

Electron transfer
Enzyme catalysis
Hydrogen transfer
Quantum tunnelling
Transition state theory

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10.1098/rsif.2006.0122

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title = "Quantum catalysis in enzymes: Beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005",

abstract = "How do enzymes work? What is the physical basis of the phenomenal rate enhancements achieved by enzymes? Do we have a theoretical framework that accounts for observed catalytic rates? These are the foremost questions - with particular emphasis on tunnelling phenomena - debated at this Discussion Meeting by the leading practitioners in the field. {\textcopyright} 2006 The Royal Society.",

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KW - Enzyme catalysis

KW - Hydrogen transfer

KW - Quantum tunnelling

KW - Transition state theory

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Quantum catalysis in enzymes: Beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005

Abstract

Keywords

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