Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?

G. G. Hanna; T. Illidge

doi:10.1016/j.clon.2016.07.014

Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?

G. G. Hanna^*, T. Illidge

^*Corresponding author for this work

The University of Manchester

Queen's University Belfast

Research output: Contribution to journal › Article › peer-review

Abstract

The goal of re-programming the host immune system to target malignancy with durable anti-tumour clinical responses has been speculated for decades. In the last decade such speculation has been transformed into reality with unprecedented and durable responses to immune checkpoint inhibitors seen in solid tumours. This mini-review considers the mechanism of action of immune modulating agents and the potential for combination with radiotherapy in the treatment of non-small cell lung cancer.

Original language	English
Pages (from-to)	726-731
Number of pages	6
Journal	Clinical Oncology
Volume	28
Issue number	11
Early online date	9 Aug 2016
DOIs	https://doi.org/10.1016/j.clon.2016.07.014
Publication status	Published - 1 Nov 2016

Keywords

Checkpoint inhibition
immunotherapy
NSCLC
radiotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.clon.2016.07.014

Cite this

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title = "Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?",

abstract = "The goal of re-programming the host immune system to target malignancy with durable anti-tumour clinical responses has been speculated for decades. In the last decade such speculation has been transformed into reality with unprecedented and durable responses to immune checkpoint inhibitors seen in solid tumours. This mini-review considers the mechanism of action of immune modulating agents and the potential for combination with radiotherapy in the treatment of non-small cell lung cancer.",

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Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?

Abstract

Keywords

UN SDGs

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