Radiotherapy for small-cell lung cancer-Where are we heading?

N. A. Bayman; H. Sheikh; B. Kularatne; P. Lorigan; F. Blackhall; N. Thatcher; C. Faivre-Finn

doi:10.1016/j.lungcan.2008.06.013

Radiotherapy for small-cell lung cancer-Where are we heading?

N. A. Bayman, H. Sheikh, B. Kularatne, P. Lorigan, F. Blackhall, N. Thatcher, C. Faivre-Finn

Research output: Contribution to journal › Article › peer-review

Abstract

Radiotherapy has an established role in the management of limited-disease small-cell lung cancer. However, essential questions related to the optimisation of thoracic radiotherapy remain unanswered including (i) optimal total dose, (ii) fractionation, (iii) timing and sequencing of radiation, (iv) volume of irradiation, and (v) concurrent chemotherapy combinations. The role of thoracic radiotherapy for extensive-disease small-cell lung cancer is more poorly understood but evidence suggests radiotherapy may have an important role in this setting. This review highlights the need for well-designed multi-national trials aimed at the optimisation and standardisation of radiotherapy for SCLC. © 2008 Elsevier Ireland Ltd. All rights reserved.

Original language	English
Pages (from-to)	307-314
Number of pages	7
Journal	Lung Cancer
Volume	63
Issue number	3
DOIs	https://doi.org/10.1016/j.lungcan.2008.06.013
Publication status	Published - Mar 2009

Keywords

Fractionation
Prophylactic cranial irradiation
Radiotherapy
Review
Small-cell lung cancer
Thoracic radiotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.lungcan.2008.06.013

Cite this

@article{a7b5415d6eef458a9ac94965c870e87a,

title = "Radiotherapy for small-cell lung cancer-Where are we heading?",

abstract = "Radiotherapy has an established role in the management of limited-disease small-cell lung cancer. However, essential questions related to the optimisation of thoracic radiotherapy remain unanswered including (i) optimal total dose, (ii) fractionation, (iii) timing and sequencing of radiation, (iv) volume of irradiation, and (v) concurrent chemotherapy combinations. The role of thoracic radiotherapy for extensive-disease small-cell lung cancer is more poorly understood but evidence suggests radiotherapy may have an important role in this setting. This review highlights the need for well-designed multi-national trials aimed at the optimisation and standardisation of radiotherapy for SCLC. {\textcopyright} 2008 Elsevier Ireland Ltd. All rights reserved.",

keywords = "Fractionation, Prophylactic cranial irradiation, Radiotherapy, Review, Small-cell lung cancer, Thoracic radiotherapy",

author = "Bayman, {N. A.} and H. Sheikh and B. Kularatne and P. Lorigan and F. Blackhall and N. Thatcher and C. Faivre-Finn",

year = "2009",

month = mar,

doi = "10.1016/j.lungcan.2008.06.013",

language = "English",

volume = "63",

pages = "307--314",

journal = "Lung Cancer",

issn = "0169-5002",