Projects per year
by combining 160 genetic parts into 115 unique biosynthetic pathways. To explore the scale-up potential of our prototype production strains, we optimized the enantioselective production of mandelic acid and hydroxymandelic acid, achieving gram-scale production in fed-batch fermenters. The high success rate in the rapid design and prototyping of microbially-produced material building
blocks reveals the potential role of biofoundries in leading the transition to sustainable materials
- synthetic biology
- industrial biotechnology
- mandelic acid
- hydroxymandelic acid
Research Beacons, Institutes and Platforms
- Manchester Institute of Biotechnology
FingerprintDive into the research topics of 'Rapid prototyping of microbial production strains for the biomanufacture of potential material monomers'. Together they form a unique fingerprint.
- 1 Finished
Scrutton, N., Azapagic, A., Balmer, A., Barran, P., Breitling, R., Delneri, D., Dixon, N., Faulon, J., Flitsch, S., Goble, C., Goodacre, R., Hay, S., Kell, D., Leys, D., Lloyd, J., Lockyer, N., Martin, P., Micklefield, J., Munro, A., Pedrosa Mendes, P., Randles, S., Salehi Yazdi, F., Shapira, P., Takano, E., Turner, N. & Winterburn, J.
14/11/14 → 13/05/20