Rates of preterm birth following antenatal maternal exposure to severe life events: A population-based cohort study

Ali Khashan; R. McNamee; K. M. Abel; P. B. Mortensen; L. C. Kenny; M. G. Pedersen; R. T. Webb; P. N. Baker

doi:10.1093/humrep/den418

Rates of preterm birth following antenatal maternal exposure to severe life events: A population-based cohort study

Ali Khashan, R. McNamee, K. M. Abel, P. B. Mortensen, L. C. Kenny, M. G. Pedersen, R. T. Webb, P. N. Baker

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Abstract

BACKGROUND: Preterm birth and other pregnancy complications have been linked to maternal stress during pregnancy. We investigated the association between maternal exposure to severe life events and risk of preterm birth. METHODS: Mothers of all singleton live births (n = 1.35 million births) in Denmark between 1 January 1979 and 31 December 2002 were linked to data on their children, parents, siblings and partners. We defined exposure as death or serious illness in close relatives in the first or second trimesters or in the 6 months before conception. Log-linear binomial regression was used to estimate the effect of exposure on preterm birth, very preterm birth and extremely preterm birth. RESULTS: There were 58 626 (4.34%) preterm births (

Original language	English
Pages (from-to)	429-437
Number of pages	8
Journal	Human Reproduction
Volume	24
Issue number	2
DOIs	https://doi.org/10.1093/humrep/den418
Publication status	Published - Feb 2009

Keywords

Maternal stress
Obstetric complications
Pregnancy
Preterm birth
Severe life events

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/humrep/den418

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abstract = "BACKGROUND: Preterm birth and other pregnancy complications have been linked to maternal stress during pregnancy. We investigated the association between maternal exposure to severe life events and risk of preterm birth. METHODS: Mothers of all singleton live births (n = 1.35 million births) in Denmark between 1 January 1979 and 31 December 2002 were linked to data on their children, parents, siblings and partners. We defined exposure as death or serious illness in close relatives in the first or second trimesters or in the 6 months before conception. Log-linear binomial regression was used to estimate the effect of exposure on preterm birth, very preterm birth and extremely preterm birth. RESULTS: There were 58 626 (4.34\%) preterm births (",

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author = "Ali Khashan and R. McNamee and Abel, \{K. M.\} and Mortensen, \{P. B.\} and Kenny, \{L. C.\} and Pedersen, \{M. G.\} and Webb, \{R. T.\} and Baker, \{P. N.\}",

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doi = "10.1093/humrep/den418",

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T1 - Rates of preterm birth following antenatal maternal exposure to severe life events: A population-based cohort study

AU - Khashan, Ali

AU - McNamee, R.

AU - Abel, K. M.

AU - Mortensen, P. B.

AU - Kenny, L. C.

AU - Pedersen, M. G.

AU - Webb, R. T.

AU - Baker, P. N.

PY - 2009/2

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N2 - BACKGROUND: Preterm birth and other pregnancy complications have been linked to maternal stress during pregnancy. We investigated the association between maternal exposure to severe life events and risk of preterm birth. METHODS: Mothers of all singleton live births (n = 1.35 million births) in Denmark between 1 January 1979 and 31 December 2002 were linked to data on their children, parents, siblings and partners. We defined exposure as death or serious illness in close relatives in the first or second trimesters or in the 6 months before conception. Log-linear binomial regression was used to estimate the effect of exposure on preterm birth, very preterm birth and extremely preterm birth. RESULTS: There were 58 626 (4.34%) preterm births (

AB - BACKGROUND: Preterm birth and other pregnancy complications have been linked to maternal stress during pregnancy. We investigated the association between maternal exposure to severe life events and risk of preterm birth. METHODS: Mothers of all singleton live births (n = 1.35 million births) in Denmark between 1 January 1979 and 31 December 2002 were linked to data on their children, parents, siblings and partners. We defined exposure as death or serious illness in close relatives in the first or second trimesters or in the 6 months before conception. Log-linear binomial regression was used to estimate the effect of exposure on preterm birth, very preterm birth and extremely preterm birth. RESULTS: There were 58 626 (4.34%) preterm births (

KW - Maternal stress

KW - Obstetric complications

KW - Pregnancy

KW - Preterm birth

KW - Severe life events

UR - https://www.scopus.com/pages/publications/58449129148

U2 - 10.1093/humrep/den418

DO - 10.1093/humrep/den418

M3 - Article

C2 - 19054778

SN - 0268-1161

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JO - Human Reproduction

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Rates of preterm birth following antenatal maternal exposure to severe life events: A population-based cohort study

Abstract

Keywords

UN SDGs

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