Recent Progress in Decarboxylative Oxidative Cross-Couplings for Biaryl Synthesis

Gregory Perry, Igor Larrosa

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The beginning of the 21st century has seen a tremendous growth in the field of decarboxylative activation. Benzoic acids are now recognised as atom-economic
    alternatives to traditional cross-coupling partners and they also benefit from being inexpensive, readily-available and shelfstable reagents. In this microreview, we discuss recent developments in the coupling of benzoic acids with either an
    arene or a second benzoic acid, a process often labelled as decarboxylative oxidative cross-coupling. These procedures hold great promise for the development of highly selective and atom-economic cross-couplings.
    Original languageEnglish
    Pages (from-to)3517-3527
    Number of pages11
    JournalEuropean Journal of Organic Chemistry
    Volume2017
    Issue number25
    Early online date26 Apr 2017
    DOIs
    Publication statusPublished - 3 Jul 2017

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