TY - JOUR
T1 - Recommendations of the International Society of Geriatric Oncology on skin cancer management in older patients
AU - Rembielak, A.
AU - Yau, T.
AU - Akagunduz, B.
AU - Aspeslagh, S.
AU - Colloca, G.
AU - Conway, A.
AU - Danwata, F.
AU - del Marmol, V.
AU - O'Shea, C.
AU - Verhaert, M.
AU - Zic, R.
AU - Livesey, D.
PY - 2023/5/1
Y1 - 2023/5/1
N2 - Introduction: Non-melanoma skin cancer (NMSC) is becoming ever more prevalent among older adults. However, older adults with NMSC are often underrepresented in clinical trials and guidelines on effective management is still unclear. The International Society of Geriatric Oncology (SIOG) created a multi-disciplinary task force to explore the potential in developing practical guidelines for the treatment of older patients with basal cell carcinoma (BCC) and skin (cutaneous) squamous cell carcinoma (cSCC). Materials and Methods: A systematic literature search to identify relevant and up-to-date literature on treatment of NMSC in older adults was conducted on various databases including MEDLINE, Embase, CINAHL, Cochrane, and PubMed. The resulting papers were discussed by an expert panel, leading to a consensus recommendation. Results: A total of 154 articles were identified for the expert panel to utilise in generating consensus recommendations. A major focus on geriatric assessment and management options including surgery, radiotherapy, systemic therapy, clinical monitoring, and medical/medicophysical therapy were reviewed for recommendations. Discussion: Patient age should not be the sole deciding factor in the management of patients with NMSC. Assessment from a multidisciplinary team (MDT) is crucial, and the decision-making process should consider the patient's lifestyle, needs, and expectations. A comprehensive geriatric assessment should also be considered. Patients should feel empowered to advocate for themselves and have their views considered a part of the MDT discussion.
AB - Introduction: Non-melanoma skin cancer (NMSC) is becoming ever more prevalent among older adults. However, older adults with NMSC are often underrepresented in clinical trials and guidelines on effective management is still unclear. The International Society of Geriatric Oncology (SIOG) created a multi-disciplinary task force to explore the potential in developing practical guidelines for the treatment of older patients with basal cell carcinoma (BCC) and skin (cutaneous) squamous cell carcinoma (cSCC). Materials and Methods: A systematic literature search to identify relevant and up-to-date literature on treatment of NMSC in older adults was conducted on various databases including MEDLINE, Embase, CINAHL, Cochrane, and PubMed. The resulting papers were discussed by an expert panel, leading to a consensus recommendation. Results: A total of 154 articles were identified for the expert panel to utilise in generating consensus recommendations. A major focus on geriatric assessment and management options including surgery, radiotherapy, systemic therapy, clinical monitoring, and medical/medicophysical therapy were reviewed for recommendations. Discussion: Patient age should not be the sole deciding factor in the management of patients with NMSC. Assessment from a multidisciplinary team (MDT) is crucial, and the decision-making process should consider the patient's lifestyle, needs, and expectations. A comprehensive geriatric assessment should also be considered. Patients should feel empowered to advocate for themselves and have their views considered a part of the MDT discussion.
KW - Basal cell carcinoma
KW - Cancer treatment
KW - Cutaneous squamous cell carcinoma
KW - Geriatric assessment
KW - Older patients
KW - Skin cancer
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-85152909846&partnerID=MN8TOARS
U2 - 10.1016/j.jgo.2023.101502
DO - 10.1016/j.jgo.2023.101502
M3 - Article
SN - 1879-4068
VL - 14
JO - Journal of Geriatric Oncology
JF - Journal of Geriatric Oncology
IS - 4
M1 - 101502
ER -
