Recruitment and treatment practices for help-seeking "prodromal" patients

Thomas H. McGlashan, Jean Addington, Tyrone Cannon, Markus Heinimaa, Patrick McGorry, Mary O'Brien, David Penn, Diana Perkins, Raimo K R Salokangas, Barbara Walsh, Scott W. Woods, Alison Yung

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The prodrome of psychosis has become a target for early identification and for treatments that address both symptoms and risk for future psychosis. Interest and activity in this realm is now worldwide. Clinical trials with rigorous methodology have only just begun, making treatment guidelines premature. Despite the sparse evidence base, treatments are currently applied to patients in the new prodromal clinics, usually treatments developed for established psychosis and modified for the prodromal phase. This communication will describe representative samplings of how treatment-seeking prodromal patients are currently recruited and treated in prodromal clinics worldwide. Recruitment includes how prodromal patients are sought, initially evaluated, apprised of their high-risk status, and informed of the risks and benefits of prodromal treatments and how their mental state is monitored over time. The treatment modalities offered (and described) include engagement, supportive therapy, case management, stress management, cognitive behavioral treatment, family-based treatment, antipsychotic pharmacotherapy, and non-antipsychotic pharmacotherapy. References for details are noted. © The Author 2007. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved.
    Original languageEnglish
    Pages (from-to)715-726
    Number of pages11
    JournalSchizophrenia Bulletin
    Volume33
    Issue number3
    DOIs
    Publication statusPublished - Sept 2007

    Keywords

    • At-risk
    • Managing
    • Schizophrenia

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