Reduced ethanol tolerance: One of the pleiotropic effects of the pep4.3 mutation in Saccharomyces cerevisiae

David A. Sugden, Stephen G. Oliver

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Yeast strains carrying the single nuclear mutation pep4.3 are deficient in the activity of a number of vacuolar hydrolases. This paper demonstrates that the pep4.3 mutation also renders yeast more sensitive to the growth inhibitory effects of ethanol. This sensitivity to ethanol is a temperature-conditional phenomenon and suggests some general effect of the pep4.3 mutation on yeast membranes. © 1983 Science and Technology Letters.
    Original languageEnglish
    Pages (from-to)419-422
    Number of pages3
    JournalBiotechnology Letters
    Volume5
    Issue number6
    DOIs
    Publication statusPublished - Jun 1983

    Research Beacons, Institutes and Platforms

    • Manchester Institute of Biotechnology

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