Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)

J. Martin Gibson; Melissa Westwood; Robert J. Young; Anne White

doi:10.1210/jc.81.2.860

Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)

J. Martin Gibson, Melissa Westwood, Robert J. Young, Anne White

Research output: Contribution to journal › Article › peer-review

Abstract

IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p

Original language	English
Pages (from-to)	860-863
Number of pages	3
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	81
Issue number	2
DOIs	https://doi.org/10.1210/jc.81.2.860
Publication status	Published - 1996

Keywords

Blood Pressure
Body Mass Index
blood: Cardiovascular Diseases
blood: Cholesterol, HDL
blood: Cholesterol, LDL
complications: Diabetes Mellitus, Type 2
Humans
blood: Insulin-Like Growth Factor Binding Protein 1
metabolism: Insulin-Like Growth Factor I
metabolism: Insulin-Like Growth Factor II
Middle Aged
Risk Factors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1210/jc.81.2.860

Cite this

@article{bebc06bc1b2c422593bbdcf95eaa6351,

title = "Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)",

abstract = "IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p",

keywords = "Blood Pressure, Body Mass Index, blood: Cardiovascular Diseases, blood: Cholesterol, HDL, blood: Cholesterol, LDL, complications: Diabetes Mellitus, Type 2, Humans, blood: Insulin-Like Growth Factor Binding Protein 1, metabolism: Insulin-Like Growth Factor I, metabolism: Insulin-Like Growth Factor II, Middle Aged, Risk Factors",

author = "Gibson, {J. Martin} and Melissa Westwood and Young, {Robert J.} and Anne White",

year = "1996",

doi = "10.1210/jc.81.2.860",

language = "English",

volume = "81",

pages = "860--863",

journal = "Journal of Clinical Endocrinology and Metabolism",

issn = "1945-7197",

publisher = "Endocrine Society",

number = "2",

}

Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM). / Gibson, J. Martin ; Westwood, Melissa; Young, Robert J. et al.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 81, No. 2, 1996, p. 860-863.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)

AU - Gibson, J. Martin

AU - Westwood, Melissa

AU - Young, Robert J.

AU - White, Anne

PY - 1996

Y1 - 1996

N2 - IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p

AB - IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p

KW - Blood Pressure

KW - Body Mass Index

KW - blood: Cardiovascular Diseases

KW - blood: Cholesterol, HDL

KW - blood: Cholesterol, LDL

KW - complications: Diabetes Mellitus, Type 2

KW - Humans

KW - blood: Insulin-Like Growth Factor Binding Protein 1

KW - metabolism: Insulin-Like Growth Factor I

KW - metabolism: Insulin-Like Growth Factor II

KW - Middle Aged

KW - Risk Factors

U2 - 10.1210/jc.81.2.860

DO - 10.1210/jc.81.2.860

M3 - Article

C2 - 8636318

SN - 1945-7197

VL - 81

SP - 860

EP - 863

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 2

ER -

Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this