Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in noninsulin dependent diabetes mellitus (NIDDM)

J M Gibson; M Westwood; R J Young; A White

Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in noninsulin dependent diabetes mellitus (NIDDM)

J M Gibson, M Westwood, R J Young, A White

Research output: Contribution to journal › Article › peer-review

Abstract

IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p

Original language	English
Pages (from-to)	860-863
Number of pages	4
Journal	Journal of Clinical Endocrinology & Metabolism
Volume	81
Issue number	2
Publication status	Published - 1996

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title = "Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in noninsulin dependent diabetes mellitus (NIDDM)",

abstract = "IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p",

author = "Gibson, {J M} and M Westwood and Young, {R J} and A White",

year = "1996",

language = "English",

volume = "81",

pages = "860--863",

journal = "Journal of Clinical Endocrinology & Metabolism",

issn = "1945-7197",

publisher = "Endocrine Society",

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T1 - Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in noninsulin dependent diabetes mellitus (NIDDM)

AU - Gibson, J M

AU - Westwood, M

AU - Young, R J

AU - White, A

PY - 1996

Y1 - 1996

N2 - IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p

AB - IGF-I and -II levels are altered in patients with atherogenic lipid profiles and may contribute to the development of macrovascular disease in NIDDM. We examined cardiovascular risk factors, IGF-I, IGF-II and IGFBP-1 in 74 NIDDM patients analysed as a whole group and according to treatment type. IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p

M3 - Article

SN - 1945-7197

VL - 81

SP - 860

EP - 863

JO - Journal of Clinical Endocrinology & Metabolism

JF - Journal of Clinical Endocrinology & Metabolism

IS - 2

ER -

Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in noninsulin dependent diabetes mellitus (NIDDM)

Abstract

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