Reducing the toll of inflammatory lung disease.

Nazia Chaudhuri, Moira K B Whyte, Ian Sabroe

    Research output: Contribution to journalArticlepeer-review


    Toll-like receptors (TLRs) are pivotal in human response to microbial stimuli. Their activation and signaling underpin much of the observed epidemiologic data generated by the hygiene hypothesis, and their contribution to infectious exacerbations of airways disease is likely to be highly important. Our growing knowledge in this field will have a significant impact on the understanding of the pathogenesis of inflammatory diseases, and TLR-based therapies are already in early clinical trials to modify atopic disease severity.
    Original languageEnglish
    Issue number5
    Publication statusPublished - May 2007


    • Inflammation
    • Lung Disease
    • TLR
    • Toll like receptors


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