Reduction in corneal volume with severity of keratoconus

Luisa Simo Mannion, Cindy Tromans, Clare O'Donnell

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Purpose: To compare the corneal volume in keratoconic and normal eyes to improve our understanding of the tissue distribution associated with the disease. Materials and Method: The Oculus Pentacam tomographer (Oculus Inc., Wetzlar, Germany) was used to analyze the corneal volume contained within discs with diameters of 3, 5, 7, and 10mm in 21 patients with keratoconus and 21 matched healthy control subjects. Results: Corneal volume was significantly decreased in the keratoconus group (keratoconus vs. control group: 3.44±0.39 vs. 4.05±0.29mm 3, 10.34±0.95 vs. 11.79±0.84mm 3, 22.80±1.73 vs. 25.26±1.74mm 3, and 57.17±3.94 vs. 61.90±4.12mm 3 for the 3-, 5-, 7-, and 10-mm diameter discs, respectively; p
    Original languageEnglish
    Pages (from-to)522-527
    Number of pages5
    JournalCurrent Eye Research
    Volume36
    Issue number6
    Publication statusPublished - Jun 2011

    Keywords

    • Cornea
    • Keratoconus
    • Pentacam
    • Scheimpflug
    • Volume

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