Reduction of selenoamides to amines using SmI2-H2O

Samuel Thurow; Eder J Lenardão; Xavier Just-Baringo; David Procter

doi:10.1021/acs.orglett.6b03325

Reduction of selenoamides to amines using SmI2-H2O

Samuel Thurow, Eder J Lenardão, Xavier Just-Baringo, David Procter

Research output: Contribution to journal › Article › peer-review

62 Downloads (Pure)

Abstract

Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.

Original language	English
Pages (from-to)	50-53
Number of pages	4
Journal	Organic Letters
Volume	19
Issue number	1
Early online date	9 Dec 2016
DOIs	https://doi.org/10.1021/acs.orglett.6b03325
Publication status	Published - 6 Jan 2017

Access to Document

10.1021/acs.orglett.6b03325

DJP-XJB-ST-rev2-manu-Dec2Accepted author manuscript, 442 KB

Cite this

@article{94f9debefcd7420aa8fcdb50dbdb4320,

title = "Reduction of selenoamides to amines using SmI2-H2O",

abstract = "Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.",

author = "Samuel Thurow and Lenard{\~a}o, {Eder J} and Xavier Just-Baringo and David Procter",

year = "2017",

month = jan,

day = "6",

doi = "10.1021/acs.orglett.6b03325",

language = "English",

volume = "19",

pages = "50--53",

journal = "Organic Letters",

issn = "1523-7052",

publisher = "American Chemical Society",

number = "1",

}

TY - JOUR

T1 - Reduction of selenoamides to amines using SmI2-H2O

AU - Thurow, Samuel

AU - Lenardão, Eder J

AU - Just-Baringo, Xavier

AU - Procter, David

PY - 2017/1/6

Y1 - 2017/1/6

N2 - Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.

AB - Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.

U2 - 10.1021/acs.orglett.6b03325

DO - 10.1021/acs.orglett.6b03325

M3 - Article

SN - 1523-7052

VL - 19

SP - 50

EP - 53

JO - Organic Letters

JF - Organic Letters

IS - 1

ER -

Reduction of selenoamides to amines using SmI2-H2O

Abstract

Access to Document

Fingerprint

Cite this