Relative preservation of 'animate' knowledge in an atypical presentation of herpes simplex virus encephalitis

Christine Rogers, Christine Lowe, S. Knapp, M. A. Lambon Ralph

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    Abstract

    A comprehensive battery of neuropsychological tests designed to assess primary cognitive functions, including language and semantic memory, was given to MG, a patient with confirmed herpes simplex virus encephalitis. MG's initial jargon aphasia resolved over time to leave her with a mild phonological impairment. She had a very mild amnesia that was worse for verbal material and a category-specific impairment of semantic memory. This latter impairment resulted in a significant anomia that was worse for manmade/artefact items than for animate kinds. Her naming difficulties were associated with a mild impairment in comprehension that was not specific to category or feature type. MRI revealed a strongly asymmetric and atypical distribution of pathology in MG with the disease affecting the left medial temporal lobe, temporal pole, left frontotemporal and temporoparietal regions. Copyright © Taylor & Francis Inc.
    Original languageEnglish
    Pages (from-to)157-166
    Number of pages9
    JournalNeurocase
    Volume11
    Issue number3
    DOIs
    Publication statusPublished - Jun 2005

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