Reply to “Does multiple intrahepatic cholangiocarcinoma worsen prognosis as “M1” stage?”; multiple primaries vs liver metastases

Angela Lamarca, Alvaro Santos‐laso, Kirsten Utpatel, Adelaida La Casta, Simone Stock, Alejandro Forner, Jorge Adeva, Trine Folseraas, Luca Fabris, Rocio Ir Macias, Marcin Krawczyk, Marek Krawczyk, Vincenzo Cardinale, Chiara Braconi, Domenico Alvaro, Matthias Evert, Jesus M. Banales, Juan W Valle

Research output: Contribution to journalLetterpeer-review

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Abstract

We thank Zhang and colleagues for their Letter to the Editor (1) regarding our work (2). Our manuscript (“Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System”(2)), suggested changes to the American Joint Committee on Cancer (AJCC) staging classification for intrahepatic cholangiocarcinoma (iCCA), by classifying “liver metastases” as stage IV rather than stage II/III in the absence/presence of lymph node metastases, respectively, as per AJCC v.8 (3).
Original languageEnglish
JournalHepatology
Early online date7 Feb 2021
DOIs
Publication statusE-pub ahead of print - 7 Feb 2021

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