(Re)solution of a protein fold without solution

    Research output: Contribution to journalArticlepeer-review


    Who needs water? The gas phase may seem an esoteric place to examine the structures of proteins, but a new study reveals that the solution fold of the protein KIX can be retained for significant time periods in a mass spectrometer. Once in this ideal laboratory environment, details of the higher order fold can be elucidated at the single amino acid level. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
    Original languageEnglish
    Pages (from-to)3120-3122
    Number of pages2
    JournalAngewandte Chemie - International Edition
    Issue number14
    Publication statusPublished - 28 Mar 2011


    • gas-phase conformations
    • mass spectrometry
    • protein structures
    • structure elucidation


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