Respiratory symptoms, lung function and cell surface markers in a group of hemp fiber processors

D Fishwick; L J Allan; A Wright; C M Barber; A D Curran

doi:10.1002/ajim.1033

Respiratory symptoms, lung function and cell surface markers in a group of hemp fiber processors

D Fishwick
, L J Allan
, A Wright
, C M Barber
, A D Curran

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Hemp dust exposure is associated with byssinosis and accelerated lung loss in longitudinal studies. The immunological changes associated with hemp dust exposure are less well understood.

METHODS: We studied a small group of current male hemp processors with a mean age of 43 years. Questionnaire data, lung function, serial FEV(1) and blood were collected from all workers.

RESULTS: In total, seven workers (64%) complained of at least one respiratory symptom (one with byssinosis). The mean percentage predicted FEV(1) was 91.5, FVC 97.7, PEF 92.1, and FEF(25-75) 79.5. Serial FEV(1) measurements in the two workers with work-related respiratory symptoms revealed a mean change in FEV(1) on the first working day of -12.9%. This contrasted with +6.25% on the last working day. Respective values for the two workers without work-related symptoms were -1.4 and +3.2%.

CONCLUSIONS: Lung function changes and abnormalities in a profile of cell surface activation markers and antibodies were noted to relate to the presence of work-related respiratory symptoms, not seen in the control group.

Original language	English
Pages (from-to)	419-25
Number of pages	7
Journal	American Journal of Industrial Medicine
Volume	39
Issue number	4
DOIs	https://doi.org/10.1002/ajim.1033
Publication status	Published - Apr 2001

Keywords

Adult
Air Pollutants, Occupational/analysis
Byssinosis/etiology
Cannabis/adverse effects
Cross-Sectional Studies
Dust/analysis
Forced Expiratory Volume/physiology
Humans
Immunoglobulin E/blood
Male
Middle Aged
Occupational Diseases/etiology
Textile Industry
Vital Capacity/physiology

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10.1002/ajim.1033

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title = "Respiratory symptoms, lung function and cell surface markers in a group of hemp fiber processors",

abstract = "BACKGROUND: Hemp dust exposure is associated with byssinosis and accelerated lung loss in longitudinal studies. The immunological changes associated with hemp dust exposure are less well understood.METHODS: We studied a small group of current male hemp processors with a mean age of 43 years. Questionnaire data, lung function, serial FEV(1) and blood were collected from all workers.RESULTS: In total, seven workers (64\%) complained of at least one respiratory symptom (one with byssinosis). The mean percentage predicted FEV(1) was 91.5, FVC 97.7, PEF 92.1, and FEF(25-75) 79.5. Serial FEV(1) measurements in the two workers with work-related respiratory symptoms revealed a mean change in FEV(1) on the first working day of -12.9\%. This contrasted with +6.25\% on the last working day. Respective values for the two workers without work-related symptoms were -1.4 and +3.2\%.CONCLUSIONS: Lung function changes and abnormalities in a profile of cell surface activation markers and antibodies were noted to relate to the presence of work-related respiratory symptoms, not seen in the control group.",

keywords = "Adult, Air Pollutants, Occupational/analysis, Byssinosis/etiology, Cannabis/adverse effects, Cross-Sectional Studies, Dust/analysis, Forced Expiratory Volume/physiology, Humans, Immunoglobulin E/blood, Male, Middle Aged, Occupational Diseases/etiology, Textile Industry, Vital Capacity/physiology",

author = "D Fishwick and Allan, \{L J\} and A Wright and Barber, \{C M\} and Curran, \{A D\}",

year = "2001",

month = apr,

doi = "10.1002/ajim.1033",

language = "English",

volume = "39",

pages = "419--25",

journal = "American Journal of Industrial Medicine",

issn = "0271-3586",

publisher = "John Wiley \& Sons Ltd",

number = "4",

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TY - JOUR

T1 - Respiratory symptoms, lung function and cell surface markers in a group of hemp fiber processors

AU - Fishwick, D

AU - Allan, L J

AU - Wright, A

AU - Barber, C M

AU - Curran, A D

PY - 2001/4

Y1 - 2001/4

N2 - BACKGROUND: Hemp dust exposure is associated with byssinosis and accelerated lung loss in longitudinal studies. The immunological changes associated with hemp dust exposure are less well understood.METHODS: We studied a small group of current male hemp processors with a mean age of 43 years. Questionnaire data, lung function, serial FEV(1) and blood were collected from all workers.RESULTS: In total, seven workers (64%) complained of at least one respiratory symptom (one with byssinosis). The mean percentage predicted FEV(1) was 91.5, FVC 97.7, PEF 92.1, and FEF(25-75) 79.5. Serial FEV(1) measurements in the two workers with work-related respiratory symptoms revealed a mean change in FEV(1) on the first working day of -12.9%. This contrasted with +6.25% on the last working day. Respective values for the two workers without work-related symptoms were -1.4 and +3.2%.CONCLUSIONS: Lung function changes and abnormalities in a profile of cell surface activation markers and antibodies were noted to relate to the presence of work-related respiratory symptoms, not seen in the control group.

AB - BACKGROUND: Hemp dust exposure is associated with byssinosis and accelerated lung loss in longitudinal studies. The immunological changes associated with hemp dust exposure are less well understood.METHODS: We studied a small group of current male hemp processors with a mean age of 43 years. Questionnaire data, lung function, serial FEV(1) and blood were collected from all workers.RESULTS: In total, seven workers (64%) complained of at least one respiratory symptom (one with byssinosis). The mean percentage predicted FEV(1) was 91.5, FVC 97.7, PEF 92.1, and FEF(25-75) 79.5. Serial FEV(1) measurements in the two workers with work-related respiratory symptoms revealed a mean change in FEV(1) on the first working day of -12.9%. This contrasted with +6.25% on the last working day. Respective values for the two workers without work-related symptoms were -1.4 and +3.2%.CONCLUSIONS: Lung function changes and abnormalities in a profile of cell surface activation markers and antibodies were noted to relate to the presence of work-related respiratory symptoms, not seen in the control group.

KW - Adult

KW - Air Pollutants, Occupational/analysis

KW - Byssinosis/etiology

KW - Cannabis/adverse effects

KW - Cross-Sectional Studies

KW - Dust/analysis

KW - Forced Expiratory Volume/physiology

KW - Humans

KW - Immunoglobulin E/blood

KW - Male

KW - Middle Aged

KW - Occupational Diseases/etiology

KW - Textile Industry

KW - Vital Capacity/physiology

U2 - 10.1002/ajim.1033

DO - 10.1002/ajim.1033

M3 - Article

C2 - 11323792

SN - 0271-3586

VL - 39

SP - 419

EP - 425

JO - American Journal of Industrial Medicine

JF - American Journal of Industrial Medicine

IS - 4

ER -

Respiratory symptoms, lung function and cell surface markers in a group of hemp fiber processors

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Keywords

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